Re: Recent revisions to QTdrugs.org Lists
On December 26, 2019, the antipsychotic drug, chlorprothixene (Truxal®) was added to the Known Risk of Torsades de Pointes (TdP) list. The antidepressant, clomipramine (Anafranil®), was moved from the list with Possible Risk of TdP to the Conditional Risk list in the following conditions: hypokalemia, hypomagnesemia, overdose and when taken with other drugs that prolong the QT interval.
On March 19, 2020, additional changes were made to QTdrugs. The antipsychotics, Lurasidone (Latuda®) and Lumateperone (Caplyta®) and the anticancer drug, Tazemetostat (Tazverik®) were added to the Possible Risk of TdP category. Cesium chloride, an ingredient in some "dietary supplements" was added to the Known Risk of TdP list. The following three appetite suppressants were added to the Special Risk category and the Drugs to Avoid in CLQTS category: Diethylpropion (Tenuate®), phendimetrazine (Bontril®) and benzphetamine (Didrex®).
Remember, the QTdrugs lists are always up-to-date and available in the CredibleMeds mobile app and can be obtained free for personal, non-commercial use by clicking these links:
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Scientific Review Committee, AZCERT, Inc.
Raymond L. Woosley, MD, PhD
Klaus Romero, MD, MS
C.Will Heise, MD
Tyler Gallo, PharmD
Jared Tate, PharmD
David Woosley, MPH