Resources for Healthcare Professionals
This section of CredibleMeds® includes tools to assist physicians, nurses, pharmacists and other healthcare professionals who play central roles in medication safety.
QT Drugs Lists: This portal includes QTdrugs.org, a list of drugs categorized by their potential to cause QT prolongation and/or torsades de pointes (TdP). Click on a drug and see if the FDA-approved label recommends ECG monitoring.
QTFactors.org - Clinical Factors Associated with Prolonged QTc and/or TdP: This is a list of clinical factors that have been associated in the medical literature with prolonged QTc and/or Torsades de Pointes (TdP).
OncoSupport™ Drug List: This is a printable list of the QTdrugs that are often prescribed for patients with cancer. It includes designation of each drug's TdP risk category.
Categories of TdP risk for drugs:
- Drugs with known risk of TdP
- Drugs with possible risk of TdP
- Drugs with conditional risk of TdP - i.e., can cause TdP under certain conditions
- Drugs to be avoided by congenital Long QT patients (drugs above plus drugs with Special Risk
The lists can be exported by all registrants as PDF. Holders of commercial use licenses can downloard Excel files and sort by: Generic Name, Brand Name, Risk Category, Pharmacologic Class, and Therapeutic Use.
Additional drug information provided when you click on a drug name:
- Information on routes of administration.
- PubMed Links: Automatically search the National Library of Medicine's PubMed databease for articles on the drug's ability to prolong the QT intervals and/or cause torsades de pointes (TdP).
- FDA label: Information on whether the drug's label has a "black box" warning for QT/arrhythmia, mentions prolonged QT/TdP or recommends ECG monitoring.
A pocket summary of the clinical effects ofantiarrhythmc drugs and their actions on the ECG, ion channels and membrane receptors. Contributed by Romero, K and Woosley, RL, Chapter 18, Clinical Pharmacology of Antiarrhythmic Drugs, Cardiovascular Therapeutics: A Companion to Braunwald's Heart Disease, Fourth Edition edited by E.M. Antman and M.S. Sabatine, 2012.