MODULE 3: Medications with Known Risk
for Prolonged QTc and TdP

QTc Risk: A Primer for Healthcare Providers

QTc Risk Clinical Decision Support: A Primer For Healthcare Providers

MODULE 3: Medications with Known Risk for Prolonged QTc and TdP

The third education module in a series of four will focus on medications with known risk for prolonged QTc intervals and torsades de pointes (TdP).  

At the conclusion of this module, you will be invited to take a short knowledge test to give you immediate feedback regarding your understanding of the provided material.

 

 

COVERED IN MODULE THREE

DRUG INDUCED SUDDEN DEATH:

This module begins with a discussion focusing on the many medications that have been removed from the market due to their association with QT prolongation and sudden cardiac death, including a discussion of the medications that are still on the market that have the side effect, owing to the fact that the benefit of using these drugs currently outweighs the risk.

THE MECHANISM OF ACTION OF DRUG-INDUCED PROLONGED QTc

The module goes on to explore the mechanism of drug-induced QTc and how drugs that can cause QT prolongation inhibit the IKr current which leads to delayed ventricular repolarization and then — when this is combined with other risk factors — can lead to severe QT prolongation and TdP.

CREDIBLEMEDS IS IN THE APPLE AND ANDROID APP STORES

Finally, the module discusses CredibleMeds as a comprehensive source for information about drug-induced QT prolongation, torsade de pointes and the features, uses, and benefits of the CredibleMeds app.

Coming Soon

MODULE 3: Medications with Known Risk for Prolonged QTc

Please enter the correct answer for each question:

Results:

1. Medications with a “Known Risk” of Torsades de Pointes are in what drug class?

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2. Which of the following is correct regarding the market status of drugs that prolong the QT interval?

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3. Which of these accurately describes medications that can prolong the QT interval?

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4. Patients with a Tisdale QTc-Risk Score value greater than 11 are considered:

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5. Which of the following medications is NOT likely to increase the QTc interval?

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This project was supported by grant R18HS026662 from the Agency for Healthcare Research and Quality. The content is solely the responsibility of the authors and does not necessarily represent the official views of the Agency for Healthcare Research and Quality.